- Mortal Kombat Trilogy (Nintendo 64): "Reptile was once thought to be the last member of an extinct race of reptilian creatures, until the appearance of Khameleon. She alone knows the truth about their history and chooses to fight on the side of Earth. Making the last survivors of their race lethal enemies."
- Armageddon (Wii): "Shao Kahn... He destroyed the realm of Zaterra - my home. My kind is all but extinct; I believe the only survivors are Reptile and myself. I have spent a lifetime hidden from view, searching for a way to kill the emperor for what he did to my world. It seemed I had been given my chance when Reptile agreed to join forces and slay him - but once again Reptile fell under Shao Kahn's influence and turned against me. I barely escaped with my life. For a long time I had given up hope. It seemed that Shao Kahn was invincible. His allies served and protected him, and those who fought against him only seemed to make him stronger. It was as if he fed on kombat itself. I wandered the realms aimlessly, uncertain of what could be done to stop him. During my journeys, camouflaged to conceal my presence, I learned from a gathering of warriors that a great weapon would present itself in Edenia. The victor of some skirmish would be granted immense power - like that of a god. More alarming was the mention that Shao Kahn himself sought this power. The emperor will not acquire it. I will find this weapon and use it to punish Shao Kahn and those who have served him. He will suffer greatly for destroying the Raptors."
Khameleon's biography and endings screens in Mortal Kombat Trilogy describe her as the last female of her race, as Reptile is the last male. They reveal that her race, the Saurians, also known as Raptors, were originally from Earthrealm, but a great war drove some of them out of that realm and killed the rest. They found a new home in another realm, which they called Zaterra or "New Earth." However, Shao Kahn eventually found it, and after defeating them in Mortal Kombat, he drove the Raptors to near extinction and then merged the realm with Outworld.
It is said that Khameleon spent an indefinite amount of time trying to find Reptile in an attempt to restore their race, although he remained unaware of her, focusing on serving Shao Kahn. Khameleon finally caught up to Reptile and told him the truth of how Kahn was responsible for the extinction of their race. However, Reptile fell under the emperor's influence once again and turned against her. Having failed in her attempts to slay Shao Kahn, she began to wander the realms contemplating a way to strike back at him. Later, during the events of Mortal Kombat: Armageddon, she learned of the battle that would occur in Edenia and the gift of ultimate power that would be granted to the victor. Distressed by the fact that Kahn was also seeking this power, Khameleon sought out to attain it for herself so as to exact revenge on him and his followers for what he did to her race.
- Mortal Kombat Trilogy: "Khameleon's former race were known as raptors. They evolved millions of years ago on Earth into intelligent creatures but fled the realm when it was destroyed in a battle between the gods. They repopulated a new realm known as Zaterra only to be driven to extinction by Shao Kahn when they lost to Outworld in Mortal Kombat. With Shao Kahn near victory against Earth, Khameleon contacts Reptile and shares the truth about their race with him. This turns him against Kahn, allowing Khameleon to lead a sneak attack against the emperor. This last battle results in the end of Shao Kahn and unification of Earth, giving Reptile and Khameleon the chance to beget a new generation of raptors.
- Armageddon: "Drinking in the power of Blaze, Khameleon's eyes glowed as she focused her wrath on Shao Kahn. The emperor would finally pay for destroying Zaterra and so too would those who served him. The pain he endured during his transformation was excruciating and Shao Kahn for the first time in his life pleaded for mercy. She granted him none. Khameleon's power transformed Shao Kahn into a Raptor, powerful like her, but subservient to her wishes. She then turned her attention to his allies and they too were transformed. But she lost control of her new found power and mistakenly mutated the forces of light as well. Khameleon now had at her command an army of powerful Raptor warriors. The might of Zaterra had finally returned."